Full Title:Microbial Pathogenesis and Control
Module Code:SCIAS7003
Credits: 7.5
Valid From:Semester 1 - 2013/14 ( September 2013 )
Module Delivered in 4 programme(s)
Module Description:Students successfully completing this module should have an understanding of beneficial and harmful microbe human interactions and the methods we employ to combat pathogens and control microorganisms. Students will apply international standard methods to isolate, enumerate and identify target microorganisms from different sources with due regard to health and safety.
Learning Outcomes:
On successful completion of this module the learner should be able to
  1. Discuss microbes as agents of infection, their virulence, pathogenesis, interactions with the host and transmission.
  2. Describe commonly encountered pathogens their sources and reservoirs, modes of transmission, associated diseases and laboratory techniques to isolate, identify and enumerate them.
  3. Summarise the major categories of microbial control and its purposes.
  4. Evaluate chemotherapeutics as microbial infection control agents.
  5. Apply microbiology procedures to the isolation, characterisation and quantification of bacterial pathogens from various sample types.

Module Content & Assessment

Indicative Content
Topic 1: Microbe-Human Interactions
Human microbiota, factors in the development of a disease, sources and transmission of microbes, epidemiology and disease populations.
Topic 2: Commensals and Pathogens
A number of microorganisms will be selected and profiled. Students will learn where to source information pertaining to reservoirs and sources/transmission/pathogenesis/ associated disease/ treatment/incidences/control/ laboratory isolation and detection/beneficial uses/legislation.
Topic 3: Microbial Growth Control
Physical, mechanical and chemical methods of microbial control. Applications of microbial control.
Topic 4: Antimicrobials: Chemotherapeutic Agents
Principles of antimicrobial therapy, mechanisms of action and major antimicrobial drug groups; acquisition of drug resistance, interactions between drugs and host, selecting and testing antimicrobial drugs, standardisation of antimicrobial techniques, establishing MIC and MBC values.
1. A series of microbes and the human body labs including: Normal skin biota, focus Staphylococci; Bacteria of the urogenital tract, focus E.coli; Bacteria of the respiratory tract, focus Streptococci; Pathogens of the gastrointestinal tract, focus Salmonella 2. Introduction to epidemiology incorporating hand hygiene studies, fomite and direct transmission of microbes and airborne transmission. 3. Investigation of microbial growth control methods including heat, cold temperatures and filtration 4. Evaluation of the efficacy of chemicals used to control growth via disc diffusion tests. 5. Selection and profiling chemotherapeutics agents for specific pathogens. 6. Establishing chemotherapeutic minimum inhibitory and minimum bactericidal concentrations.
Teaching and Learning Strategy
Lectures: Blended and flexible learning will be used throughout. This will take the form of face to face interactive lecture sessions complemented by online resources (webcasts, podcasts, screencasts, video links etc) and online interactive activities (learn smart study assignments). Group and peer learning will be facilitated in class through the use of various classroom assessment techniques which will promote deep learning and enable feedback. Students will be directed to relevant sections of appropriate text to reinforce material covered in lectures.
Assessment Breakdown%
Course Work50.00%
End of Module Formal Examination50.00%

Full Time

Course Work
Assessment Type Assessment Description Outcome addressed % of total Marks Out Of Pass Marks Assessment Date Duration
Class Test Students will complete an interactive on-line exam consisting of a series of multiple choice, true and false, fill in the blank, short answer questions, diagram matching and labelling. Students can prepare for this exam by accessing specific interactive on-line study quizzes. 1,2 15.00 0 0 Week 7 0
Continuous Assessment Students will conduct research and subsequently apply this information to trace and map the pathway of infection for a pathogen of their choice. Data will be presented in flow diagram format. 1,2,4 10.00 0 0 Week 12 0
Practical/Skills Evaluation Students will focus on improving their core microbiological technical skills and apply them to the investigation of various sample types encountered in clinical and industrial microbiology. Submission of reports sheets or detailed reports on selected practicals will demonstrate the students ability to record, analyse and discuss data, acknowledge limitations and draw conclusions with reference to theory developed in lectures. Completion of interactive virtual labs will reinforce key concepts. 2,3,4,5 25.00 0 0 Every Week 0
No Project
No Practical
End of Module Formal Examination
Assessment Type Assessment Description Outcome addressed % of total Marks Out Of Pass Marks Assessment Date Duration
Formal Exam End-of-Semester Final Examination 1,2,3,4 50.00 0 0 End-of-Semester 0

DKIT reserves the right to alter the nature and timings of assessment


Module Workload & Resources

Workload: Full Time
Workload Type Workload Description Hours Frequency Average Weekly Learner Workload
Lecture No Description 3.00 Every Week 3.00
Practical No Description 3.00 Every Week 3.00
Directed Reading No Description 2.00 Every Week 2.00
Independent Study No Description 3.00 Every Week 3.00
Total Weekly Learner Workload 11.00
Total Weekly Contact Hours 6.00
This course has no Part Time workload.
Recommended Book Resources
  • Talaro, K.P. 2011, Foundations in Microbiology, Basic Principles, 8th Ed., McGraw-Hill [ISBN: 978-0071316736]
  • Sherlock Orla 2012, Practical Microbiology Laboratory Manual 2, DkIT
Supplementary Book Resources
  • Tortora, Funke, Case. 2012, Microbiology, an Introduction, 11th Ed., Longman Publications [ISBN: 978-0321733603]
  • Bauman 2012, Microbiology with Diseases by Taxonomy, 2nd Ed., Pearson [ISBN: 978-0321667663]
  • Madigan, M T.Martinko, Dunlap, Clark. 2008, Brock Biology of Microorganisms, 12th Ed., Pearson [ISBN: 978-0132324601]
This module does not have any article/paper resources
Other Resources

Module Delivered in

Programme Code Programme Semester Delivery
DK_SENVI_8 Bachelor of Science (Honours) in Environmental Bioscience 4 Mandatory
DK_SAPBI_7 Bachelor of Science in Applied Bioscience 4 Mandatory
659 Bachelor of Science in Environmental Bioscience 4 Mandatory
Dk_SAPBI_6 Higher Certificate in Science 4 Mandatory